ブラックジャックスプリットとは

 Tohoku University Tohoku Medical Megabank Organization (ToMMo)2024.05.31 1.   Yonezawa Yudai, Takahashi Ippei, Ohseto Hisashi, et al. Genome-wide association study of nausea and vomiting during pregnancy in Japan: the TMM BirThree Cohort Study. BMC Pregnancy and Childbirth. 2024; 24 (1): 209. doi:10.1186/s12884-024-06376-4   2.   Takayama Jun, Makino Satoshi, Funayama Takamitsu, et al. A fine‐scale genetic map of the Japanese population. Clinical Genetics. 2024; : . doi:10.1111/cge.14536   3.   Ohseto Hisashi, Takahashi Ippei, Narita Akira, et al. Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory. Depression and Anxiety. 2024; 2024 : 1-13. doi:10.1155/2024/6622666   4.   Noda Aoi, Obara Taku, Matsuzaki Fumiko, et al. Risk of Major Congenital Malformations Associated with the Use of Japanese Traditional (Kampo) Medicine Containing Ephedra During the First Trimester of Pregnancy. Drugs - Real World Outcomes. 2024; : . doi:10.1007/s40801-023-00411-0   5.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal social isolation and behavioral problems in preschool children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Child & Adolescent Psychiatry. 2024; 33 (3): 761-769. doi:10.1007/s00787-023-02199-4   6.   Noda Aoi, Obara Taku, Shirota Matsuyuki, et al. Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Journal of Clinical Pharmacology. 2024; : . doi:10.1007/s00228-024-03685-7   7.   Chiba Ippei, Nakaya Naoki, Kogure Mana, et al. Associations between housing and psychological damage by earthquake and modifiable risk factors for dementia in general older adults: Tohoku Medical Megabank community‐based cohort study. Geriatrics & Gerontology International. 2024; : . doi:10.1111/ggi.14867   8.   Takase Masato, Nakaya Naoki, Tanno Kozo, et al. Relationship between traditional risk factors for hypertension and systolic blood pressure in the Tohoku Medical Megabank Community-based Cohort Study. Hypertension Research. 2024; : . doi:10.1038/s41440-024-01582-1   9.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. The association between blood pressure control in women during pregnancy and adverse perinatal outcomes: the TMM BirThree Cohort Study. Hypertension Research. 2024; 47 (5): 1216-1222. doi:10.1038/s41440-023-01570-x   10.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. The association between depressive symptoms and masked hypertension in participants with normotension measured at research center. Hypertension Research. 2024; 47 (3): 586-597. doi:10.1038/s41440-023-01484-8   11.   Yamada Mitsuhiro, Takase Masato, Nakaya Kumi, et al. Fractional exhaled nitric oxide distribution and its relevant factors in the general adult population and its healthy subpopulation. Journal of Allergy and Clinical Immunology: Global. 2024; 3 (3): 100253. doi:10.1016/j.jacig.2024.100253   12.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Relationships of Fat Mass Index and Fat-Free Mass Index with Low-Density Lipoprotein Cholesterol Levels in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2024; : 64535. doi:10.5551/jat.64535   13.   Hozawa Atsushi, Nakaya Kumi, Nakaya Naoki, et al. Progress report of the Tohoku Medical Megabank Community-Based Cohort Study: Study profile of the repeated center-based survey during second period in Miyagi Prefecture. Journal of Epidemiology. 2024; : JE20230241. doi:10.2188/jea.JE20230241   14.   Ishikuro Mami, Nishimura Tomoko, Iwata Hiroyoshi, et al. Association between infertility treatment and hypertensive disorders of pregnancy in the Japan Birth Cohort Consortium: a meta-analysis. Journal of Human Hypertension. 2024; 38 (2): 187-190. doi:10.1038/s41371-023-00890-2   15.   Nakaya Kumi, Nakaya Naoki, Kogure Mana, et al. Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study. Journal of Neurogastroenterology and Motility. 2024; 30 (2): 208-219. doi:10.5056/jnm23090   16.   Sato Mitsuharu, Hishinuma Eiji, Matsukawa Naomi, et al. Dietary habits and plasma lipid concentrations in a general Japanese population. Metabolomics. 2024; 20 (2): 34. doi:10.1007/s11306-024-02087-1   17.   Tadaka Shu, Kawashima Junko, Hishinuma Eiji, et al. jMorp: Japanese Multi-Omics Reference Panel update report 2023. Nucleic Acids Research. 2024; 52 (D1): D622-D632. doi:10.1093/nar/gkad978   18.   Mizuno Satoshi, Wagata Maiko, Nagaie Satoshi, et al. Development of phenotyping algorithms for hypertensive disorders of pregnancy (HDP) and their application in more than 22,000 pregnant women. Scientific Reports. 2024; 14 (1): 6292. doi:10.1038/s41598-024-55914-9   19.   Aoki Yu-ichi, Taguchi Keiko, Anzawa Hayato, et al. Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals. The Journal of Biochemistry. 2024; : . doi:10.1093/jb/mvae008   20.   Kobayashi Masayuki, Ishikuro Mami, Obara Taku, Kuriyama Shinichi. Weight‐for‐age z ‐scores of Japanese children using the World Health Organization Child Growth Standards. Acta Paediatrica. 2023; 112 (4): 776-778. doi:10.1111/apa.16662   21.   Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal postnatal bonding disorder and developmental delays in children: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Archives of Women's Mental Health. 2023; 26 (2): 219-226. doi:10.1007/s00737-023-01298-0   22.   Kudo Hisaaki, Ishida Noriko, Nobukuni Takahiro, et al. Detection and Correction of Sample Misidentifications in a Biobank Using the MassARRAY System and Genomic Information. Biopreservation and Biobanking. 2023; : . doi:10.1089/bio.2022.0211   23.   Nakai Taku, Iwamura Yuma, Kato Koichiro, et al. Drugs activating hypoxia-inducible factors correct erythropoiesis and hepcidin levels via renal EPO induction in mice. Blood Advances. 2023; 7 (15): 3793-3805. doi:10.1182/bloodadvances.2023009798   24.   Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Association between frequency of breakfast intake before and during pregnancy and infant birth weight: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Pregnancy and Childbirth. 2023; 23 (1): 268. doi:10.1186/s12884-023-05603-8   25.   Mizuno Satoshi, Nagaie Satoshi, Tamiya Gen, et al. Establishment of the early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study. BMC Pregnancy and Childbirth. 2023; 23 (1): 628. doi:10.1186/s12884-023-05919-5   26.   Murakami Keiko, Aida Jun, Kuriyama Shinichi, Hashimoto Hideki. Associations of health literacy with dental care use and oral health status in Japan. BMC Public Health. 2023; 23 (1): 1074. doi:10.1186/s12889-023-15866-7   27.   Ohneda Kinuko, Hamanaka Yohei, Kawame Hiroshi, et al. Returning individual genomic results to population-based cohort study participants with BRCA1/2 pathogenic variants. Breast Cancer. 2023; 30 (1): 110-120. doi:10.1007/s12282-022-01404-7   28.   Tsuchiya Masami, Obara Taku, Kikuchi Masafumi, Mano Nariyasu. The prevalence of end-of-life chemotherapy and targeted therapy in Japan, assessed using a health claims database. Cancer Chemotherapy and Pharmacology. 2023; 91 (6): 501-506. doi:10.1007/s00280-023-04535-6   29.   Shimizu Takanori, Iwama Noriyuki, Tokunaga Hideki, et al. Precautions during Direct Oral Anticoagulant Introduction in Gynecologic Malignancies: A Single-Center Retrospective Cohort Study. Cancers. 2023; 15 (4): 1132. doi:10.3390/cancers15041132   30.   Shinoda Genki, Nagaoka Yudai, Ueno Fumihiko, et al. Association between being Overweight in Young Childhood and during School Age and Puberty. Children. 2023; 10 (5): 909. doi:10.3390/children10050909   31.   Oikawa Daiki, Fukui Kohei, Aoki Yuichi, et al. Enterocloster alcoholdehydrogenati sp. nov., a Novel Bacterial Species Isolated from the Feces of a Patient with Alcoholism. Current Microbiology. 2023; 80 (5): 187. doi:10.1007/s00284-023-03285-1   32.   Ueno Fumihiko, Murakami Keiko, Nagai Masato, et al. Difficulties in Accessing Medication Records at the Time of a Large-Scale Disaster. Disaster Medicine and Public Health Preparedness. 2023; 17 : e370. doi:10.1017/dmp.2022.301   33.   Makiguchi Miaki, Shimizu Makiko, Yokota Yuka, et al. Variants of Flavin-Containing Monooxygenase 3 Found in Subjects in an Updated Database of Genome Resources. Drug Metabolism and Disposition. 2023; 51 (7): 884-891. doi:10.1124/dmd.123.001310   34.   Murakami Keiko, Kuriyama Shinichi, Hashimoto Hideki. Economic, cognitive, and social paths of education to health-related behaviors: evidence from a population-based study in Japan. Environmental Health and Preventive Medicine. 2023; 28 (1): 22-00178. doi:10.1265/ehpm.22-00178   35.   Sato Shiho, Yu Zhiqian, Sakai Mai, et al. Decreased β‐hydroxybutyrate and ketogenic amino acid levels in depressed human adults. European Journal of Neuroscience. 2023; 57 (6): 1018-1032. doi:10.1111/ejn.15931   36.   Obara Taku, Ishikuro Mami, Ueno Fumihiko, et al. Antihypertensive drug use during pregnancy in Japan. Hypertension Research. 2023; 46 (2): 548-549. doi:10.1038/s41440-022-01101-0   37.   Tanaka Kosuke, Nishigori Hidekazu, Watanabe Zen, et al. Secondhand smoke exposure is associated with the risk of hypertensive disorders of pregnancy: the Japan Environment and Children’s Study. Hypertension Research. 2023; 46 (4): 834-844. doi:10.1038/s41440-022-01144-3   38.   Hatanaka Rieko, Nakaya Naoki, Kogure Mana, et al. The risk of withdrawal from hypertension treatment in coastal areas after the Great East Japan Earthquake: the TMM CommCohort Study. Hypertension Research. 2023; 46 (12): 2718-2728. doi:10.1038/s41440-023-01454-0   39.   Takahashi Ippei, Obara Taku, Ishikuro Mami, et al. Screen Time at Age 1 Year and Communication and Problem-Solving Developmental Delay at 2 and 4 Years. JAMA Pediatrics. 2023; 177 (10): 1039. doi:10.1001/jamapediatrics.2023.3057   40.   Taira Makiko, Mugikura Shunji, Mori Naoko, et al. Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study: Rationale, Design, and Background. JMA Journal. 2023; 6 (3): 246-264. doi:10.31662/jmaj.2022-0220   41.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal postnatal bonding disorder and emotional/behavioral problems in preschool children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 325 : 582-587. doi:10.1016/j.jad.2023.01.044   42.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Traumatic experiences of the Great East Japan Earthquake and postpartum depressive symptoms: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Affective Disorders. 2023; 320 : 461-467. doi:10.1016/j.jad.2022.09.139   43.   Tokioka Sayuri, Nakaya Naoki, Nakaya Kumi, et al. Association of Central Blood Pressure and Carotid Intima Media Thickness with New-Onset Hypertension in People with High Normal Blood Pressure. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64151. doi:10.5551/jat.64151   44.   Takase Masato, Nakamura Tomohiro, Nakaya Naoki, et al. Associations between the Combined Fat Mass Index and Fat-Free Mass Index with Carotid Intima-Media Thickness in a Japanese Population: The Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (3): 63523. doi:10.5551/jat.63523   45.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (10): 64039. doi:10.5551/jat.64039   46.   Takase Masato, Nakaya Naoki, Nakamura Tomohiro, et al. Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Atherosclerosis and Thrombosis. 2023; 30 (12): 64425. doi:10.5551/jat.64425   47.   Shiokawa Nanako, Okazaki Tatsuma, Suzukamo Yoshimi, et al. Association between Low Forced Vital Capacity and High Pneumonia Mortality, and Impact of Muscle Power. Journal of Clinical Medicine. 2023; 12 (9): 3272. doi:10.3390/jcm12093272   48.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Factors Associated With Postpartum Smoking Relapse Among Women Who Quit in Early Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (1): JE20200609. doi:10.2188/jea.JE20200609   49.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. Relation of Disaster Exposure With Maternal Characteristics and Obstetric Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology. 2023; 33 (3): JE20210052. doi:10.2188/jea.JE20210052   50.   Sugawara Yuka, Kato Hideki, Nagasaki Masao, et al. CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome. Journal of Human Genetics. 2023; 68 (6): 427-430. doi:10.1038/s10038-023-01129-1   51.   Takase Masato, Yamada Mitsuhiro, Nakamura Tomohiro, et al. Association between lung function and hypertension and home hypertension in a Japanese population: the Tohoku Medical Megabank Community-Based Cohort Study. Journal of Hypertension. 2023; 41 (3): 443-452. doi:10.1097/HJH.0000000000003356   52.   Hishinuma Eiji, Shimada Muneaki, Matsukawa Naomi, et al. Identification of predictive biomarkers for diagnosis and radiation sensitivity of uterine cervical cancer using wide‐targeted metabolomics. Journal of Obstetrics and Gynaecology Research. 2023; 49 (8): 2109-2117. doi:10.1111/jog.15709   53.   Murakami Keiko, Obara Taku, Ishikuro Mami, et al. Associations of Education and Income with Secondhand Smoke Exposure Among Non-smoking Pregnant Women in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Maternal and Child Health Journal. 2023; 27 (7): 1238-1246. doi:10.1007/s10995-023-03648-x   54.   Fukudo Shin, Nakaya Kumi, Muratsubaki Tomohiko, et al. Characteristics of disorders of gut–brain interaction in the Japanese population in the Rome Foundation Global Epidemiological Study. Neurogastroenterology & Motility. 2023; 35 (6): . doi:10.1111/nmo.14581   55.   Ogawa Sayaka, Hayashida Masaki, Tayama Jun, et al. Preventive Effects of Group Cognitive Behavioral Therapy in First-Year University Students at Risk for Depression: A Non-Randomized Controlled Trial. Perceptual and Motor Skills. 2023; 130 (2): 790-807. doi:10.1177/00315125231153778   56.   Matsuda Hinako, Yamazaki Yumi, Moriyoshi Eiko, et al. Apoplast-Localized β-Glucosidase Elevates Isoflavone Accumulation in the Soybean Rhizosphere. Plant And Cell Physiology. 2023; 64 (5): 486-500. doi:10.1093/pcp/pcad012   57.   Ono Chiaki T., Yu Zhiqian, Obara Taku, et al. Association between low levels of anti‐inflammatory cytokines during pregnancy and postpartum depression. Psychiatry and Clinical Neurosciences. 2023; 77 (8): 434-441. doi:10.1111/pcn.13566   58.   Aizawa Misato, Murakami Keiko, Yonezawa Yudai, et al. Associations between sugar-sweetened beverages before and during pregnancy and offspring overweight/obesity in Japanese women: the TMM BirThree Cohort Study. Public Health Nutrition. 2023; 26 (6): 1222-1229. doi:10.1017/S1368980023000307   59.   Ishikuro Mami, Obara Taku, Murakami Keiko, et al. Infertility Treatment and Hypertension in Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Reproductive Medicine. 2023; 4 (2): 89-99. doi:10.3390/reprodmed4020010   60.   Seo Kanako, Takayanagi Naoto, Sudo Motoki, et al. Association between daily gait speed patterns and cognitive impairment in community-dwelling older adults. Scientific Reports. 2023; 13 (1): 2783. doi:10.1038/s41598-023-29805-4   61.   Suzuki Tetsuya, Morioka Shinichiro, Yamamoto Kei, et al. Nasopharyngeal SARS-CoV-2 may not be dispersed by a high-flow nasal cannula. Scientific Reports. 2023; 13 (1): 2669. doi:10.1038/s41598-023-29740-4   62.   Akaishi Tetsuya, Misu Tatsuro, Fujihara Kazuo, et al. White blood cell count profiles in anti-aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorder and anti-myelin oligodendrocyte glycoprotein antibody-associated disease. Scientific Reports. 2023; 13 (1): 6481. doi:10.1038/s41598-023-33827-3   63.   Murakami Keiko, Noda Aoi, Ishikuro Mami, et al. Maternal social isolation in the perinatal period and early childhood development: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Social Psychiatry and Psychiatric Epidemiology. 2023; 58 (11): 1593-1601. doi:10.1007/s00127-023-02498-w   64.   Kobayashi Tomoko, Kobayashi Mika, Minegishi Naoko, et al. Design and Progress of Child Health Assessments at Community Support Centers in the Birth and Three-Generation Cohort Study of the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2023; 259 (2): 2022.J103. doi:10.1620/tjem.2022.J103   65.   小暮真奈, 寳澤篤. ナトリウム/カリウム（Na/K）比に関する知見と今後の展開. 日本循環器病予防学会誌. 2023; 58 (1): 22-30.   66.   Kawaguchi Chikana, Murakami Keiko, Ishikuro Mami, et al. Cumulative exposure to maternal psychological distress in the prenatal and postnatal periods and atopic dermatitis in children: findings from the TMM BirThree Cohort Study. BMC Pregnancy and Childbirth. 2022; 22 (1): 242. doi:10.1186/s12884-022-04556-8   67.   Yonezawa Yudai, Ueno Fumihiko, Obara Taku, et al. Fruit and vegetable consumption before and during pregnancy and developmental delays in offspring aged 2 years in Japan. British Journal of Nutrition. 2022; 127 (8): 1250-1258. doi:10.1017/S0007114521002154   68.   Otsuki Akihito, Okamura Yasunobu, Ishida Noriko, et al. Construction of a trio-based structural variation panel utilizing activated T lymphocytes and long-read sequencing technology. Communications Biology. 2022; 5 (1): 991. doi:10.1038/s42003-022-03953-1   69.   Yonezawa Yudai, Obara Taku, Yamashita Takahiro, et al. Grain consumption before and during pregnancy and birth weight in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. European Journal of Clinical Nutrition. 2022; 76 (2): 261-269. doi:10.1038/s41430-021-00939-w   70.   Kogure Mana, Nakamura Tomohiro, Tsuchiya Naho, et al. Consideration of the reference value and number of measurements of the urinary sodium-to-potassium ratio based on the prevalence of untreated home hypertension: TMM Cohort Study. Hypertension Research. 2022; 45 (5): 866-875. doi:10.1038/s41440-021-00843-7   71.   Satoh Michihiro, Murakami Takahisa, Obara Taku, Metoki Hirohito. Time-series analysis of blood pressure changes after the guideline update in 2019 and the coronavirus disease pandemic in 2020 using Japanese longitudinal data. Hypertension Research. 2022; 45 (9): 1408-1417. doi:10.1038/s41440-022-00961-w   72.   Ohseto Hisashi, Ishikuro Mami, Obara Taku, et al. Preeclampsia prediction model using the dipstick test for proteinuria during early gestation. Hypertension Research in Pregnancy. 2022; 10 (3): HRP2022-002. doi:10.14390/jsshp.HRP2022-002   73.   Nagata Shohei, Nakaya Tomoki, Hanibuchi Tomoya, et al. Development of a method for walking step observation based on large-scale GPS data. International Journal of Health Geographics. 2022; 21 (1): 10. doi:10.1186/s12942-022-00312-5   74.   Yu Zhiqian, Matsukawa Naomi, Saigusa Daisuke, et al. Plasma metabolic disturbances during pregnancy and postpartum in women with depression. iScience. 2022; 25 (12): 105666. doi:10.1016/j.isci.2022.105666   75.   Ohneda Kinuko, Hiratsuka Masahiro, Kawame Hiroshi, et al. A Pilot Study for Return of Individual Pharmacogenomic Results to Population-Based Cohort Study Participants. JMA Journal. 2022; 5 (2): . doi:10.31662/jmaj.2021-0156   76.   Takase Masato, Nakamura Tomohiro, Hirata Takumi, et al. Association between fat mass index, fat‐free mass index and hemoglobin A1c in a Japanese population: The Tohoku Medical Megabank Community‐based Cohort Study. Journal of Diabetes Investigation. 2022; 13 (5): 858-867. doi:10.1111/jdi.13729   77.   Itabashi Fumi, Hirata Takumi, Kogure Mana, et al. Combined Associations of Liver Enzymes and Obesity With Diabetes Mellitus Prevalence: The Tohoku Medical Megabank Community-based Cohort Study. Journal of Epidemiology. 2022; 32 (5): JE20200384. doi:10.2188/jea.JE20200384   78.   Sugawara Junichi, Ishikuro Mami, Obara Taku, et al. Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of epidemiology. 2022; 32 (2): 69-79. doi:10.2188/jea.JE20200338   79.   Kawame Hiroshi, Fukushima Akimune, Fuse Nobuo, et al. The return of individual genomic results to research participants: design and pilot study of Tohoku Medical Megabank Project. Journal of Human Genetics. 2022; 67 (1): 9-17. doi:10.1038/s10038-021-00952-8   80.   Aizawa Misato, Murakami Keiko, Takahashi Ippei, et al. Skipping breakfast during pregnancy and hypertensive disorders of pregnancy in Japanese women: the Tohoku medical megabank project birth and three-generation cohort study. Nutrition Journal. 2022; 21 (1): 71. doi:10.1186/s12937-022-00822-9   81.   Fuse Nobuo, Sakurai Miyuki, Motoike Ikuko N., et al. Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan. Ophthalmology Science. 2022; 2 (1): 100113. doi:10.1016/j.xops.2022.100113   82.   Kanno I., Hasegawa K., Nakamura T., et al. Relationship between the housing coldness/warmth evaluation by CASBEE Housing Health Checklist and psychological distress based on TMM Community-Based Cohort Study: a cross-sectional analysis. Public Health. 2022; 208 : 98-104. doi:10.1016/j.puhe.2022.05.003   83.   Murakami Keiko, Ishikuro Mami, Obara Taku, et al. Maternal personality and postpartum mental disorders in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Scientific Reports. 2022; 12 (1): 6400. doi:10.1038/s41598-022-09944-w   84.   Iwama Noriyuki, Obara Taku, Ishikuro Mami, et al. Risk scores for predicting small for gestational age infants in Japan: The TMM birthree cohort study. Scientific Reports. 2022; 12 (1): 8921. doi:10.1038/s41598-022-12892-0   85.   Kikuchi Daisuke, Obara Taku, Usuzaki Takuma, et al. Evaluating folic acid supplementation among Japanese pregnant women with dietary intake of folic acid lower than 480 µg per day: results from TMM BirThree Cohort Study. The Journal of Maternal-Fetal & Neonatal Medicine. 2022; 35 (5): 964-969. doi:10.1080/14767058.2020.1739020   86.   Ishikuro Mami, Noda Aoii, Murakami Keiko, et al. Families’ Health after the Great East Japan Earthquake: Findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2022; 256 (2): 93-101. doi:10.1620/tjem.256.93   87.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Maternal personality and alcohol use during pregnancy in Japan: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Addictive Behaviors. 2021; 122 : 107020. doi:10.1016/j.addbeh.2021.107020   88.   Yamashita Takahiro, Murakami Keiko, Obara Taku, et al. Living environments long-term after the Great East Japan Earthquake and nutritional intake among recent mothers. Asia Pacific journal of clinical nutrition. 2021; 30 (4): 651-661. doi:10.6133/apjcn.202112_30(4).0012   89.   Nakaya Naoki, Xie Tian, Scheerder Bart, et al. Spousal similarities in cardiometabolic risk factors: A cross-sectional comparison between Dutch and Japanese data from two large biobank studies. Atherosclerosis. 2021; 334 : 85-92. doi:10.1016/j.atherosclerosis.2021.08.037   90.   Uchida Yasuo, Higuchi Tomoya, Shirota Matsuyuki, et al. Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia. Biological and Pharmaceutical Bulletin. 2021; 44 (6): 804-815. doi:10.1248/bpb.b20-01043   91.   Murakami Keiko, Obara Taku, Ishikuro Mami, et al. Associations of education and work status with alcohol use and cessation among pregnant women in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. BMC Public Health. 2021; 21 (1): 1400. doi:10.1186/s12889-021-11461-w   92.   Nishimoto Yuka, Tsubono Yoshitaka, Kogure Mana, et al. The prevalence of current smokers and alcohol drinkers among cancer survivors and subjects with no history of cancer among participants in a community‐based cardiometabolic screening program in Miyagi prefecture, Japan: a comparison with nationally repres. Cancer Medicine. 2021; 10 (24): 9000-9011. doi:10.1002/cam4.4364   93.   Takase Masato, Nakamura Tomohiro, Tsuchiya Naho, et al. Association between the combined fat mass and fat-free mass index and hypertension: The Tohoku Medical Megabank Community-based Cohort Study. Clinical and Experimental Hypertension. 2021; 43 (7): 610-621. doi:10.1080/10641963.2021.1925681   94.   Yamada Mitsuhiro, Motoike Ikuko N., Kojima Kaname, et al. Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator. Communications Biology. 2021; 4 (1): 1288. doi:10.1038/s42003-021-02813-8   95.   Saigusa Daisuke, Matsukawa Naomi, Hishinuma Eiji, Koshiba Seizo. Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics. Drug Metabolism and Pharmacokinetics. 2021; 37 : 100373. doi:10.1016/j.dmpk.2020.11.008   96.   Saito Sakae, Aoki Yuichi, Tamahara Toru, et al. Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project. Frontiers in Cellular and Infection Microbiology. 2021; 10 : . doi:10.3389/fcimb.2020.604596   97.   Ogishima Soichi, Nagaie Satoshi, Mizuno Satoshi, et al. dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project. Human Genome Variation. 2021; 8 (1): 44. doi:10.1038/s41439-021-00175-5   98.   Hirata Takumi, Kogure Mana, Tsuchiya Naho, et al. Impacts of the urinary sodium-to-potassium ratio, sleep efficiency, and conventional risk factors on home hypertension in a general Japanese population. Hypertension Research. 2021; 44 (7): 858-865. doi:10.1038/s41440-021-00628-y   99.   Murakami Keiko, Ishikuro Mami, Ueno Fumihiko, et al. Social Predictors of Continued and Indoor Smoking Among Partners of Non-smoking Pregnant Women: The TMM BirThree Cohort Study. Journal of Epidemiology. 2021; 31 (12): JE20200313. doi:10.2188/jea.JE20200313   100.   Hozawa Atsushi, Tanno Kozo, Nakaya Naoki, et al. Study profile of the tohoku medical megabank community-based cohort study. Journal of Epidemiology. 2021; 31 (1): 65-76. doi:10.2188/jea.JE20190271   101.   Otsuki Akihito, Okamura Yasunobu, Aoki Yuichi, et al. Identification of Dominant Transcripts in Oxidative Stress Response by a Full-Length Transcriptome Analysis. Molecular and Cellular Biology. 2021; 41 (2): 1-18. doi:10.1128/MCB.00472-20   102.   Takayama Jun, Tadaka Shu, Yano Kenji, et al. Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference. Nature Communications. 2021; 12 (1): 226. doi:10.1038/s41467-020-20146-8   103.   Tadaka Shu, Hishinuma Eiji, Komaki Shohei, et al. jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population. Nucleic Acids Research. 2021; 49 (D1): D536-D544. doi:10.1093/nar/gkaa1034   104.   Ishikuro Mami, Murakami Keiko, Yokozeki Fumiya, et al. Hypertension in pregnancy as a possible factor for child autistic behavior at two years old. Pregnancy Hypertension. 2021; 25 (8): 88-90. doi:10.1016/j.preghy.2021.05.020   105.   Sakurai-Yageta Mika, Kumada Kazuki, Gocho Chinatsu, et al. Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs. The Journal of Biochemistry. 2021; 170 (3): 399-410. doi:10.1093/jb/mvab060   106.   Hishinuma Eiji, Shimada Muneaki, Matsukawa Naomi, et al. Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer. Toxins. 2021; 13 (7): 461. doi:10.3390/toxins13070461   107.   髙瀬 雅仁, 五十嵐 有香, 中谷 直樹, et al. 東日本大震災に伴う災害による健康影響に関する文献レビュー. 日本循環器病予防学会誌. 2021; 56 (3): 244-257.   108.   Okuda Hiroshi, Okamoto Koji, Abe Michiaki, et al. Genome-wide association study identifies new loci for albuminuria in the Japanese population. Clinical and Experimental Nephrology. 2020; 24 (8): 1-9. doi:10.1007/s10157-020-01884-x   109.   Koshiba Seizo, Motoike Ikuko N., Saigusa Daisuke, et al. Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population. Communications Biology. 2020; 3 (1): 662. doi:10.1038/s42003-020-01383-5   110.   Ishida Noriko, Aoki Yuichi, Katsuoka Fumiki, et al. Landscape of electrophilic and inflammatory stress-mediated gene regulation in human lymphoblastoid cell lines. Free Radical Biology and Medicine. 2020; 161 : 71-83. doi:10.1016/j.freeradbiomed.2020.09.023   111.   Kuniyoshi Yasutaka, Obara Taku, Ishikuro Mami, et al. Effectiveness of seasonal inactivated influenza vaccination in Japanese schoolchildren: an epidemiologic study at the community level. Human Vaccines & Immunotherapeutics. 2020; 16 (2): 295-300. doi:10.1080/21645515.2019.1655833   112.   Wagata Maiko, Kogure Mana, Nakaya Naoki, et al. Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis. Hypertension Research. 2020; 43 (11): 1277-1283. doi:10.1038/s41440-020-0463-8   113.   Kogure Mana, Hirata Takumi, Nakaya Naoki, et al. Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study. Hypertension Research. 2020; 43 (1): 62-71. doi:10.1038/s41440-019-0335-2   114.   Hirata Takumi, Nakamura Tomohiro, Kogure Mana, et al. Reduced sleep efficiency, measured using an objective device, was related to an increased prevalence of home hypertension in Japanese adults. Hypertension Research. 2020; 43 (1): 23-29. doi:10.1038/s41440-019-0329-0   115.   Kuriyama Shinichi, Metoki Hirohito, Kikuya Masahiro, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. International Journal of Epidemiology. 2020; 49 (1): 18-19m. doi:10.1093/ije/dyz169   116.   Shirota Matsuyuki, Saigusa Daisuke, Yamashita Riu, et al. Longitudinal plasma amino acid profiling with maternal genomic background throughout human pregnancy. Medical Mass Spectrometry. 2020; 4 (1): 36-49. doi:10.24508/mms.2020.06.001   117.   Yonezawa Yudai, Obara Taku, Yamashita Takahiro, et al. Fruit and vegetable consumption before and during pregnancy and birth weight of new-borns in Japan: the Tohoku medical megabank project birth and three-generation cohort study. Nutrition Journal. 2020; 19 (1): 80. doi:10.1186/s12937-020-00595-z   118.   Kojima Kaname, Tadaka Shu, Katsuoka Fumiki, et al. A genotype imputation method for de-identified haplotype reference information by using recurrent neural network. PLOS Computational Biology. 2020; 16 (10): e1008207. doi:10.1371/journal.pcbi.1008207   119.   Nishizawa Ayako, Kumada Kazuki, Tateno Keiko, et al. Analysis of HLA-G long-read genomic sequences in mother–offspring pairs with preeclampsia. Scientific Reports. 2020; 10 (1): 20027. doi:10.1038/s41598-020-77081-3   120.   Usuzaki Takuma, Ishikuro Mami, Metoki Hirohito, et al. Comparison among research, home, and office blood pressure measurements for pregnant women: The TMM BirThree Cohort Study. The Journal of Clinical Hypertension. 2020; 22 (11): 2004-2013. doi:10.1111/jch.14050   121.   Tsuboi Akito, Matsui Hiroyuki, Shiraishi Naru, et al. Design and Progress of Oral Health Examinations in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2020; 251 (2): 97-115. doi:10.1620/tjem.251.97   122.   Nagami Fuji, Kuriki Miho, Koreeda Sachie, et al. Public Relations and Communication Strategies in Construction of Large-Scale Cohorts and Biobank: Practice in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2020; 250 (4): 253-262. doi:10.1620/tjem.250.253   123.   Takahashi Yuta, Ueki Masao, Yamada Makoto, et al. Improved metabolomic data-based prediction of depressive symptoms using nonlinear machine learning with feature selection. Translational Psychiatry. 2020; 10 (1): 157. doi:10.1038/s41398-020-0831-9   124.   Takahashi Yuta, Ueki Masao, Tamiya Gen, et al. Machine learning for effectively avoiding overfitting is a crucial strategy for the genetic prediction of polygenic psychiatric phenotypes. Translational Psychiatry. 2020; 10 (1): 294. doi:10.1038/s41398-020-00957-5   125.   Sakurai-Yageta Mika, Kawame Hiroshi, Kuriyama Shinichi, et al. A training and education program for genome medical research coordinators in the genome cohort study of the Tohoku Medical Megabank Organization. BMC Medical Education. 2019; 19 (1): 297. doi:10.1186/s12909-019-1725-5   126.   Sugawara Junichi, Ochi Daisuke, Yamashita Riu, et al. Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy. BMJ Open. 2019; 9 (2): e025939. doi:10.1136/bmjopen-2018-025939   127.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Prefabricated Temporary Housing and Eczema or Respiratory Symptoms in Schoolchildren after the Great East Japan Earthquake: The ToMMo Child Health Study. Disaster Medicine and Public Health Preparedness. 2019; 13 (5-6): 905-911. doi:10.1017/dmp.2019.8   128.   Yamaguchi-Kabata Yumi, Yasuda Jun, Uruno Akira, et al. Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals. Human Genetics. 2019; 138 (4): 389-409. doi:10.1007/s00439-019-01998-7   129.   Tadaka Shu, Katsuoka Fumiki, Ueki Masao, et al. 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome. Human Genome Variation. 2019; 6 (1): 28. doi:10.1038/s41439-019-0059-5   130.   Nagasaki Masao, Kuroki Yoko, Shibata Tomoko F., et al. Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing. Human Genome Variation. 2019; 6 (1): 27. doi:10.1038/s41439-019-0057-7   131.   Sakurai Rieko, Ueki Masao, Makino Satoshi, et al. Outlier detection for questionnaire data in biobanks. International Journal of Epidemiology. 2019; 48 (4): 1305-1315. doi:10.1093/ije/dyz012   132.   Fuse Nobuo, Sakurai-Yageta Mika, Katsuoka Fumiki, et al. Establishment of Integrated Biobank for Precision Medicine and Personalized Healthcare: The Tohoku Medical Megabank Project. JMA Journal. 2019; 2 (2): 113-122. doi:10.31662/jmaj.2019-0014   133.   Yasuda Jun, Kinoshita Kengo, Katsuoka Fumiki, et al. Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. The Journal of Biochemistry. 2019; 165 (2): 139-158. doi:10.1093/jb/mvy096   134.   Mimori Takahiro, Yasuda Jun, Kuroki Yoko, et al. Construction of full-length Japanese reference panel of class I HLA genes with single-molecule, real-time sequencing. The Pharmacogenomics Journal. 2019; 19 (2): 136-146. doi:10.1038/s41397-017-0010-4   135.   Minegishi Naoko, Nishijima Ichiko, Nobukuni Takahiro, et al. Biobank Establishment and Sample Management in the Tohoku Medical Megabank Project. The Tohoku Journal of Experimental Medicine. 2019; 248 (1): 45-55. doi:10.1620/tjem.248.45   136.   Kuniyoshi Yasutaka, Kikuya Masahiro, Miyashita Masako, et al. Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study. Allergology International. 2018; 67 (4): 481-486. doi:10.1016/j.alit.2018.02.009   137.   Yasuda Jun, Katsuoka Fumiki, Danjoh Inaho, et al. Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project. BMC Genomics. 2018; 19 (1): 551. doi:10.1186/s12864-018-4942-0   138.   Koshiba Seizo, Motoike Ikuko, Saigusa Daisuke, et al. Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project. Genes to Cells. 2018; 23 (6): 406-417. doi:10.1111/gtc.12588   139.   Yamaguchi-Kabata Yumi, Yasuda Jun, Tanabe Osamu, et al. Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals. Journal of Human Genetics. 2018; 63 (2): 213-230. doi:10.1038/s10038-017-0347-1   140.   Tadaka Shu, Saigusa Daisuke, Motoike Ikuko N., et al. jMorp: Japanese Multi Omics Reference Panel. Nucleic Acids Research. 2018; 46 (D1): D551-D557. doi:10.1093/nar/gkx978   141.   Hachiya Tsuyoshi, Narita Akira, Ohmomo Hideki, et al. Genome-wide analysis of polymorphism × sodium interaction effect on blood pressure identifies a novel 3′-BCL11B gene desert locus. Scientific Reports. 2018; 8 (1): 14162. doi:10.1038/s41598-018-32074-1   142.   Ishikuro Mami, Obara Taku, Osanai Tamae, et al. Strategic Methods for Recruiting Grandparents: The Tohoku Medical Megabank Birth and Three-Generation Cohort Study. The Tohoku Journal of Experimental Medicine. 2018; 246 (2): 97-105. doi:10.1620/tjem.246.97   143.   Takai-Igarashi Takako, Kinoshita Kengo, Nagasaki Masao, et al. Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design. BMC Medical Informatics and Decision Making. 2017; 17 (1): 100. doi:10.1186/s12911-017-0494-5   144.   Pan Xiaoqing, Nariai Naoki, Fukuhara Noriko, et al. Monitoring of minimal residual disease in early T‐cell precursor acute lymphoblastic leukaemia by next‐generation sequencing. British Journal of Haematology. 2017; 176 (2): 318-321. doi:10.1111/bjh.13948   145.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. Psychological Distress and the Risk of Withdrawing From Hypertension Treatment After an Earthquake Disaster. Disaster Medicine and Public Health Preparedness. 2017; 11 (2): 179-182. doi:10.1017/dmp.2016.102   146.   Yamamoto Kayono, Hachiya Tsuyoshi, Fukushima Akimune, et al. Population-based biobank participants’ preferences for receiving genetic test results. Journal of Human Genetics. 2017; 62 (12): 1037-1048. doi:10.1038/jhg.2017.81   147.   Kikuya Masahiro. Development of a Questionnaire Method of Screening for Citrin Deficiency in Schoolchildren. JPCD. 2017; 4 : 1-4. doi:10.17303/jpcd.2017.4.101   148.   Tsuchiya Naho, Nakaya Naoki, Nakamura Tomohiro, et al. Impact of social capital on psychological distress and interaction with house destruction and displacement after the Great East Japan Earthquake of 2011. Psychiatry and Clinical Neurosciences. 2017; 71 (1): 52-60. doi:10.1111/pcn.12467   149.   Ueki Masao, Tamiya Gen. Smooth-Threshold Multivariate Genetic Prediction with Unbiased Model Selection. Genetic Epidemiology. 2016; 40 (3): 233-243. doi:10.1002/gepi.21958   150.   Kuriyama Shinichi, Yaegashi Nobuo, Nagami Fuji, et al. The Tohoku Medical Megabank Project: Design and Mission. Journal of Epidemiology. 2016; 26 (9): 493-511. doi:10.2188/jea.JE20150268   151.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. Unemployment risk among individuals undergoing medical treatment for chronic diseases. Occupational Medicine. 2016; 66 (2): 143-149. doi:10.1093/occmed/kqv159   152.   Yamagishi Junya, Sato Yukuto, Shinozaki Natsuko, et al. Comparison of Boiling and Robotics Automation Method in DNA Extraction for Metagenomic Sequencing of Human Oral Microbes. PLOS ONE. 2016; 11 (4): e0154389. doi:10.1371/journal.pone.0154389   153.   Saigusa Daisuke, Okamura Yasunobu, Motoike Ikuko N., et al. Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery. PLOS ONE. 2016; 11 (8): e0160555. doi:10.1371/journal.pone.0160555   154.   Ishikuro Mami, Nakaya Naoki, Obara Taku, et al. Public Attitudes toward an Epidemiological Study with Genomic Analysis in the Great East Japan Earthquake Disaster Area. Prehospital and Disaster Medicine. 2016; 31 (3): 330-334. doi:10.1017/S1049023X16000182   155.   Koshiba Seizo, Motoike Ikuko, Kojima Kaname, et al. The structural origin of metabolic quantitative diversity. Scientific Reports. 2016; 6 (1): 31463. doi:10.1038/srep31463   156.   Nakaya Naoki, Narita Akira, Tsuchiya Naho, et al. Partners’ Ongoing Treatment for Chronic Disease and the Risk of Psychological Distress after the Great East Japan Earthquake. The Tohoku Journal of Experimental Medicine. 2016; 239 (4): 307-314. doi:10.1620/tjem.239.307   157.   相澤 弥生, 小林 朋子, 川目 裕. 網羅的ゲノム解析における偶発的所見を含む遺伝情報の結果の返却に関する我が国の現状と課題の検討 - 米国臨床遺伝・ゲノム学会 (ACMG) の偶発的所見取り扱いに関する推奨からの考察 -. 日本遺伝カウンセリング学会誌. 2016; 37(3) : 105 - 126. https://www.google.co.jp/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0ahUKEwiFlJC5zsnWAhVHm5QKHRZ8ASQQFggnMAA&url=https%3A%2F%2Fmol.medicalonline.jp%2Farchive%2Fselect%3Fjo%3Ddg8genco&usg=AFQjCNH2UmhYVh7WSBNqQlB4q9hwJq4L3A   158.   Mimori Takahiro, Nariai Naoki, Kojima Kaname, et al. Estimating copy numbers of alleles from population-scale high-throughput sequencing data. BMC Bioinformatics. 2015; 16 (S1): S4. doi:10.1186/1471-2105-16-S1-S4   159.   Nariai Naoki, Kojima Kaname, Saito Sakae, et al. HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data. BMC Genomics. 2015; 16 (S2): S7. doi:10.1186/1471-2164-16-S2-S7   160.   Nakaya Naoki, Nakamura Tomohiro, Tsuchiya Naho, et al. The Association Between Medical Treatment of Physical Diseases and Psychological Distress After the Great East Japan Earthquake: The Shichigahama Health Promotion Project. Disaster Medicine and Public Health Preparedness. 2015; 9 (4): 374-381. doi:10.1017/dmp.2015.52   161.   Yamaguchi-Kabata Yumi, Nariai Naoki, Kawai Yosuke, et al. iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing. Human Genome Variation. 2015; 2 (1): 15050. doi:10.1038/hgv.2015.50   162.   Kawai Yosuke, Mimori Takahiro, Kojima Kaname, et al. Japonica array: improved genotype imputation by designing a population-specific SNP array with 1070 Japanese individuals. Journal of Human Genetics. 2015; 60 (10): 581-587. doi:10.1038/jhg.2015.68   163.   Nagasaki Masao, Yasuda Jun, Katsuoka Fumiki, et al. Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nature Communications. 2015; 6 (1): 8018. doi:10.1038/ncomms9018   164.   Sato Yukuto, Yamagishi Junya, Yamashita Riu, et al. Inter-Individual Differences in the Oral Bacteriome Are Greater than Intra-Day Fluctuations in Individuals. PLOS ONE. 2015; 10 (6): e0131607. doi:10.1371/journal.pone.0131607   165.   Miyashita Masako, Kikuya Masahiro, Yamanaka Chizuru, et al. Eczema and Asthma Symptoms among Schoolchildren in Coastal and Inland Areas after the 2011 Great East Japan Earthquake: The ToMMo Child Health Study. The Tohoku Journal of Experimental Medicine. 2015; 237 (4): 297-305. doi:10.1620/tjem.237.297   166.   Kikuya Masahiro, Miyashita Masako, Yamanaka Chizuru, et al. Protocol and Research Perspectives of the ToMMo Child Health Study after the 2011 Great East Japan Earthquake. The Tohoku Journal of Experimental Medicine. 2015; 236 (2): 123-130. doi:10.1620/tjem.236.123   167.   Katsuoka Fumiki, Yokozawa Junji, Tsuda Kaoru, et al. An efficient quantitation method of next-generation sequencing libraries by using MiSeq sequencer. Analytical Biochemistry. 2014; 466 (466C): 27-29. doi:10.1016/j.ab.2014.08.015   168.   Sato Yukuto, Kojima Kaname, Nariai Naoki, et al. SUGAR: graphical user interface-based data refiner for high-throughput DNA sequencing. BMC Genomics. 2014; 15 (1): 664. doi:10.1186/1471-2164-15-664   169.   Nariai Naoki, Kojima Kaname, Mimori Takahiro, et al. TIGAR2: sensitive and accurate estimation of transcript isoform expression with longer RNA-Seq reads. BMC Genomics. 2014; 15 (S10): S5. doi:10.1186/1471-2164-15-S10-S5   170.   Motoike Ikuko N, Matsumoto Mitsuyo, Danjoh Inaho, et al. Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population. BMC Genomics. 2014; 15 (1): 673. doi:10.1186/1471-2164-15-673   171.   Kojima Kaname, Nariai Naoki, Mimori Takahiro, et al. HapMonster: A Statistically Unified Approach for Variant Calling and Haplotyping Based on Phase-Informative Reads. Lecture Notes in Computer Science. 2014; 8542 : 107-118. doi:10.1007/978-3-319-07953-0_9   172.   Ohtsuki Tomohiko, Nariai Naoki, Kojima Kaname, et al. SVEM: A Structural Variant Estimation Method Using Multi-mapped Reads on Breakpoints. Lecture Notes in Computer Science. 2014; 8542 : 208-219. doi:10.1007/978-3-319-07953-0_17   173.   Kojima Kaname, Nariai Naoki, Mimori Takahiro, et al. A statistical variant calling approach from pedigree information and local haplotyping with phase informative reads. Bioinformatics. 2013; 29 (22): 2835-2843. doi:10.1093/bioinformatics/btt503   174.   Nariai Naoki, Hirose Osamu, Kojima Kaname, Nagasaki Masao. TIGAR: transcript isoform abundance estimation method with gapped alignment of RNA-Seq data by variational Bayesian inference. Bioinformatics. 2013; 29 (18): 2292-2299. doi:10.1093/bioinformatics/btt381   175.   Mimori Takahiro, Nariai Naoki, Kojima Kaname, et al. iSVP: an integrated structural variant calling pipeline from high-throughput sequencing data. BMC Systems Biology. 2013; 7 (S6): S8. doi:10.1186/1752-0509-7-S6-S8